There have been penalties for those who looked the other way when Epstein was convicted of child sex offences and decided to maintain relationships with the financier — but not for the British ambassador to Washington, reveals SOLOMON HUGHES
The legacy of colonialism in treating ‘sleeping sickness’
A new drug is showing promise for an old disease — but elimination will require more than pharmaceuticals, explain ROX MIDDLETON, LIAM SHAW and JOEL HELLEWELL
Found in tropical Africa, when a tsetse fly carrying parasites bites a person, the parasitic cells enter the person’s blood. When the parasites progress to the brain they cause muscle weakness, tremors, and reversed or disturbed sleep patterns.
Labour’s new Treasury unit will ‘challenge unnecessary regulation’ by forcing nominally independent bodies like Ofwat to bend to business demands — exactly what Iain Anderson’s corporate clients wanted, writes SOLOMON HUGHES
DR DYLAN MURPHY looks at a Big Brother Watch report which exposes the government as an enabler of DWP secret spying on benefit claimants
The EU faces a critical choice: will it remain in the shadow of an increasingly unreliable US ally, or will it forge its own path in a multilateral world where co-operation with China is essential, asks MARC VANDEPITTE as leaders meet for the EU-China Summit
A lot of discussion about how the left should currently organise – including debate on whether the Green Party is a useful vehicle for advance – runs the risk of refusing to engage with or learn from the reasons the left was defeated previously, argues KEVIN OVENDEN
For Egypt trade trumps the Israeli genocide of the Palestinians, but how long can the country’s ‘misleaders’ – and others in the region – continue their indifference against the popular will of their own people, asks ROGER McKENZIE
HUMAN African trypanosomiasis, abbreviated as HAT, is a potentially fatal disease caused by infection with a parasite, Trypanosoma brucei. The parasite is transmitted between humans via the bite of the tsetse fly. When a tsetse fly carrying parasites bites a person, the parasitic cells enter the person’s blood. There, the parasite’s cells start to divide into two and multiply.
This initial “blood stage” infection can cause non-specific symptoms such as fever, headaches, and joint pains. These general symptoms are difficult to diagnose as trypanosomiasis. Proper diagnosis requires looking at blood that has been treated with a special staining chemical under a microscope so that the parasite cells stand out.
This lack of easily noticeable symptoms has meant that many HAT cases go undetected. This is particularly concerning because, left untreated, chronic blood-stage infections will progress to the “neurological stage.” This is when the parasites cross the blood-brain barrier and infect the brain and spinal fluid.
When the parasites progress to the brain they cause much more severe symptoms such as muscle weakness, tremors, and confusion. Infected individuals also experience very disturbed sleeping patterns, leading to the common nickname of “sleeping sickness” for HAT cases. People’s experiences include insomnia, bouts of sudden sleepiness during the day, or a totally reversed sleeping pattern, where they are awake all night and feel sleepy all day.
The neurological stage also produces psychological changes in the host, producing emotional instability and psychosis. Left untreated, it will eventually lead to death. Unfortunately, once the parasites have crossed the blood-brain barrier, treatment is more difficult.
Treatment of late-stage HAT involves drug delivery over the course of 10 days in hospital, which is often not possible for people in rural locations where the disease is most likely to have gone untreated. The drugs for the neurological stage are also more toxic with greater side effects.
Though diseases like HAT and malaria had existed in tropical regions for a long time, colonialism worsened them by increasing the movement of workers between tropical regions and port cities, cramming people together. One epidemic in Uganda beginning in 1901 raged for 20 years, killing an estimated 200,000 people.
More from this author
What’s behind the stubborn gender gap in Stem disciplines ask ROX MIDDLETON, LIAM SHAW and MIRIAM GAUNTLETT in their column Science and Society
While politicians condemned fascist bombing of Spanish civilians in 1937, they ignored identical RAF tactics across the colonies. Today’s aerial warfare continues this pattern of applying different moral standards based on geography and race, write ROX MIDDLETON, LIAM SHAW and MIRIAM GAUNTLETT
The distinction between domestic and military drones is more theoretical than practical, write ROX MIDDLETON, LIAM SHAW and MIRIAM GAUNTLETT
Nature's self-reconstruction is both intriguing and beneficial and as such merits human protection, write ROX MIDDLETON, LIAM SHAW and MIRIAM GAUNTLETT
